By M.J. Janse, M.R. Rosen (auth.)
This ebook accommodates the main up-to date details on the topic of mechanisms and therapy of cardiac arrhythmia. the various issues mentioned during this textual content mirror very lately undertaken learn instructions together with genetics of arrhythmias, telephone signalling molecules as strength healing objectives and trafficking to the membrane. those new techniques and implementations of anti-arrhythmic treatment derive from many a long time of study as defined within the first bankruptcy through exceptional Professors Michael Rosen (Columbia collage) and Michiel Janse (University of Amsterdam). The textual content covers alterations in techniques to treatment over the years, arrhythmias in a number of cardiac areas and over many scales, from gene to protein to cellphone to tissue to organ.
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Extra resources for Basis and Treatment of Cardiac Arrhythmias
Circulation 95:1658–1660 Pick A, Langendorf R (1979) Interpretation of complex arrhythmias. Lea and Febiger, Philadelphia Pogwizd SM, Corr PB (1987) Reentrant and nonreentrant mechanisms contribute to arrhythmogenesis during early myocardial ischemia: results using three-dimensional mapping. Circ Res 61:352–371 Porter WT (1894) On the results of ligation of the coronary arteries. J Physiol (Lond) 15:121–138 Prevost JL, Battelli F (1899) Sur quelques effets des décharges électriques sur le coeur des Mammifères.
The cardiac pump is thrown out of gear, and the last of its vital energy is dissipated in a violent and prolonged turmoil of fruitless activity in the ventricular walls” (McWilliam 1889). McWilliam’s ideas were largely ignored for many decades. g. ventricular ﬁbrillation)—a view fundamentally different from those entertained up to that time. Little attention was given to the new view for many years” [MacWilliam 1923 (his name in 1923 was spelled MacWilliam rather than McWilliam)]. Little attention was given to his views for many more years.
In the diagram, the ordinate is a time scale indicating the moment of activation of N1 and N2 during a regularly paced beat from the atrium. The abscissa is a time scale indicating the moments of activation of N1 and N2 during steady-state tachycardia (hatched band, solid circles) and during the interpolated atrial premature beats (open circles). The time scale of the diagram is not the same as that of the recordings. See text for further discussion. (Reproduced from Janse et al. 1971) This is what Mines meant by upsetting the reciprocal rhythm by the interpolation of extrasystoles.